Researchers at Uppsala University have adapted Cell Painting, a widely used imaging method in drug discovery, to look at individual cells inside small 3D clusters of cancer cells. Two drugs that looked almost identical in ordinary flat cell cultures behaved differently in 3D, and the team linked the difference to how each drug switches on the cell’s p53 stress response.
A new model has made it possible to estimate how the backbones of some of the first animals on land could and could not move using sturgeon as a material analogue. These results disprove a long-standing hypothesis that changes in early tetrapod anatomy as they moved onto land gave them improved neck mobility.
Many people who survive a heart attack will later develop heart failure due to the scarring that occurs as the heart heals. Researchers at Uppsala University are now presenting a new type of biological treatment that is administered directly into the damaged blood vessel and stimulates healing. In the study, they also demonstrate how a new PET (Positron Emission Tomography) method can be used to i
Researchers at Uppsala University have calculated that the Sun contains 55 per cent more silver than previously estimated. The results are based on more realistic modelling of the Sun’s atmosphere and resolve a long-standing problem of missing silver in the solar system.
Researchers at Uppsala University have discovered a completely new fungal species, which they chose to name after the King of Sweden. The species has been given the Latin name Semicentenialea rex, which means fifty-year anniversary of the King. It is the first known representative of a new class of fungi that will be called Semicentenialomycetes.
Two people with the same BMI may have entirely different risks of developing type 2 diabetes, depending on the biological mechanisms underlying their overweight. Some types of obesity increase a person’s risk of diabetes, while others do not influence the risk at all, or even appear to be protective. Now researcher's describe the different molecular processes that drive these differences.
A new type of hip replacement implant reduces the risk of joint dislocation after surgery by 70 per cent. This is the finding of a new study involving 1,600 patients across 44 hospitals in Sweden and the UK, as published in The Lancet. The new implant consists of a small ball encased in a much larger plastic ball, which gives better stability.
