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Difficult decisions led to unequal vaccination rates

There was a significant difference in the speed with which different groups were vaccinated against COVID-19. One explanation could be that people absorb information and make decisions in different ways. A new study shows that among people with the highest cognitive ability, 80% had been vaccinated within 50 days. Among those with the lowest cognitive ability, it took 180 days to achieve the same

New spatial omics method created

Researchers at Uppsala University, Stockholm University and KTH have managed to create a new spatial omics method. By combining two complex techniques that are usually used separately – mass spectrometry imaging (MSI) and spatially resolved transcriptomics (SRT) – they have taken an important step in research on biological tissues. The study is published in the Nature Biotechnology.

Publication of 2,000 canine genomes provides toolkit for translational research

An international research consortium has generated and analysed 2000 canine genomes. The resulting advanced genetics toolkit can now be used to answer complex biological questions, spanning dog domestication, genetic differences in breed morphology, behaviour and disease susceptibility, as well as the evolution and structure of the genome.

Example of pottery roughly 6,000 years old from the Lublin-Volhynian agrarian culture, Książnice 2, Poland. Photo credit: Stanisław Wilk

New research links early Europeans’ cultural and genetic development over several thousand years

A new DNA study has nuanced the picture of how different groups intermingled during the European Stone Age, but also how certain groups of people were actually isolated. The study was carried out by researchers at Uppsala University working with an international team of researchers, who produced new genetic data from 56 Central and Eastern European individuals from the Stone Age.

New method to identify mutations in childhood brain tumors

Researchers at Uppsala university have developed a new method to find mutations in brain tumors in children. They could also show that the mutations identified by them changes how cancer cells respond to a cancer drug. These findings could lead to better diagnostics and more individualized treatment of children with brain tumors. The study is published in the journal PNAS.

Gut bacteria linked to fatty deposits in heart arteries

In a major Swedish study, researchers have discovered a link between the levels of certain bacteria living in the gut and coronary atherosclerotic plaques. Such atherosclerotic plaques constitute a major cause of heart attacks. The study was led by researchers at Uppsala University and Lund University and the findings have now been published in the scientific journal Circulation.

View of the part of the enzyme that controls the temperature optimum. The loop region that is shown in dark blue is from the Antarctic bacterium and that shown in red from the pig enzyme.

Scientists designed new enzyme using Antarctic bacteria and computer calculations

For the first time, researchers have succeeded in predicting how to change the optimum temperature of an enzyme using large computer calculations. A cold-adapted enzyme from an Antarctic bacterium was used as a basis. The study is to be published in the journal Science Advances and is a collaboration between researchers at Uppsala University and the University of Tromsø.

High BMI elevates risk of several rheumatic diseases – but not equally for everyone

A new study by Uppsala University shows that a higher body mass index (BMI) increases the risk of five different rheumatic diseases: rheumatism, osteoarthritis, gout, psoriatic arthritis and inflammatory spondylitis. The researchers also noted that BMI was a stronger risk factor for women compared to men in terms of gout and psoriatic arthritis. The study will be presented in the journal Arthritis

Hand-wringing characterised debate around begging

It was the inability of both the political right and left to see and take responsibility for the systemic failures of the welfare society that led to the so-called “begging debate” in the early 2010s. This inability meant that they gave a free pass to the Sweden Democrats, who were alone able to formulate both the problem and their solution.These are some of the conclusions in a new monograph.

New study links contraceptive pills and depression

Women who used combined contraceptive pills were at greater risk of developing depression than women who did not, according to a new study. The pills increased women’s risk by 73 per cent during the first two years of use. “Since we only investigated combined contraceptive pills in this study, we cannot draw conclusions about other contraceptive options", says leading researcher Uppsala University

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Uppsala University - quality, knowledge, and creativity since 1477

Founded in 1477, Uppsala University is the oldest university in Sweden. With more than 50,000 students and 7,500 employees in Uppsala and Visby, we are a broad university with research in social sciences, humanities, technology, natural sciences, medicine and pharmacology. Our mission is to conduct education and research of the highest quality and relevance to society on a long-term basis. Uppsala University is regularly ranked among the world’s top universities.

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