Scientists at Uppsala University have discovered a hitherto unknown function of blood platelets in cancer. In mouse models, these platelets have proved to help preserve the vascular barrier which makes blood-vessel walls selectively impermeable, thereby reducing the spread of tumour cells to other parts of the body. The study is published in the journal Cancer Research.
A research team at Uppsala University has resurrected several billion-year-old enzymes and reprogrammed them to catalyse completely different chemical reactions than their modern versions can manage. The method can be used to develop sustainable solutions within biotechnology, such as for enzyme bioreactors or to chemically degrade environmental toxins.
Researchers at Uppsala University have developed a method for identifying functional mutations and their effect on genes relevant to the development of glioblastoma – a malignant brain tumour with a very poor prognosis. The study is published in Genome Biology.
Patients taking part in clinical trials do not receive better treatment than other patients. This is the conclusion of a new study led from Uppsala University and published in peer-reviewed journal BMC Cancer, which confirms the results of an earlier study from 2004.
Artificial intelligence (AI) may be an aid to interpreting ECG results, helping healthcare staff to diagnose diseases that affect the heart. Researchers at Uppsala University and heart specialists in Brazil have developed an AI that automatically diagnoses atrial fibrillation and five other common ECG abnormalities just as well as a cardiologist.
Individuals with social anxiety disorder have markedly different personality traits than others. Emotional instability and introversion are hallmarks, according to a new study from Uppsala University published in PLOS ONE.
Pool frogs infected with the parasitic chytrid fungus Batrachochytrium dendrobatidis range over shorter distances. This is the conclusion of a study conducted by researchers at Uppsala University and the Swedish University of Agricultural Sciences (SLU), who have investigated how the fungus affects the mobility of the red-listed pool frog along the Uppland coast.
The quicker someone completes the long distance cross-country ski race Vasaloppet, the lower the risk of them developing high blood pressure. This is the conclusion of a new study conducted by researchers at Uppsala University published in the online scientific journal Circulation.
The balance between the neurotransmitters serotonin and dopamine may affect whether a person develops social anxiety disorder. Previous research has mainly focused on either the serotonin or the dopamine system individually. Now researchers at Uppsala University have demonstrated the existence of a previously unknown link between the two. The results are published in Molecular Psychiatry.
Researchers at Uppsala University have made a breakthrough in the understanding of energy storage in sodium ion batteries by using ultra-high-resolution X-ray spectroscopy. These findings will aid the development of new materials for future battery generations with significantly higher and more stable voltages than previously, shows an article published in the research journal Nature.
Medication prescribed for a certain type of epilepsy may offer a new method for treating malignant infantile brain tumours. A specific mTOR inhibitor has the ability to cross the blood–brain barrier to both reach and attack the tumour at source. This has been demonstrated by researchers from Uppsala University, in collaboration with US and UK colleagues, and is published in Cell Stem Cell.
What is consciousness? What does it mean to be ‘aware’, and how is our consciousness connected to the physical brain? A recent thesis from Uppsala University explores the philosophical aspects of the issue, and proposes a solution: the ‘intrinsic consciousness’ theory.
“We need to combine empirical and conceptual work to assess the significant issues raised by these developments in brain resear
How variable are gene transcripts and proteins, the molecules of life, across the tissues and organs of the human body? Furthermore, how variable are they within the same tissue type from different people? These questions are the focus of a new study led by researchers from Uppsala University, which is published in NAR Genomics and Bioinformatics.
An international experimental research team led from HPSTAR, China and Uppsala University, Sweden, have used experimental research as well as theory to understand high-pressure structural phase transitions in hydrogen which could give rise to metallisation and could even result in superconductivity. The findings were published this week in the online edition of Nature.
Lena Claessonn-Welsh's researcher group from Uppsala University, has revealed for the first time a mechanism for how new blood vessels are formed and have shown the importance of this mechanism for embryo survival and organ function. The results could be developed to control the formation of new blood vessels in different diseases. The new study is published in the journal EMBO Reports.
Physicists at Uppsala University have identified how to distinguish between true and ‘fake’ Majorana states in one of the most commonly used experimental setups, by means of supercurrent measurements. This theoretical study is a crucial step for advancing the field of topological superconductors and applications of Majorana states for robust quantum computers. New experiments are expected next.
A single amino acid change in the light-sensing rhodopsin protein played a critical role when herring adapted to the red-shifted light environment in the Baltic Sea, shows an study by an international team of scientists, led by researchers from Uppsala University, which is published in PNAS. Remarkably about one third of all fish living in brackish or freshwater carry the same change.
Bacterial ribosomes need a single-stranded ribosome binding site (RBS) to initiate protein synthesis, whereas stable RNA structure blocks initiation. Paradoxically, structured mRNAs can nevertheless be efficiently translated. Researchers at Uppsala University have now elucidated the anatomy of a "standby" site and its requirements, to overcome RNA structure problems for translation.
The majority of women who undergo surgery for suspected ovarian cancer do not have cancer. A novel blood test developed by researchers at Uppsala University and University of Gothenburg, now offers the possibility of more precise diagnostics. This could lead to a reduction in unnecessary surgery and to earlier detection and treatment for affected women. (Communications Biology).
New data from the Uppsala Conflict Data Program (UCDP), Uppsala University shows that in 2018 the number of fatalities in organised violence reached the lowest level in seven years. However, the large share of internationalised conflicts, to which external states contribute troops, worries researchers. These conflicts tend to be both bloodier and longer.