The amount of time a blood sample used for medical research has been stored at a biobank may affect the test results as much as the blood sample provider’s age. These are the findings of a new study from Uppsala University, published in journal EBioMedicine. Until now, medical research has taken into account age, sex and health factors, but it turns out that storage time is just as important.
Cell lines are cultured cells that are commonly used in medical research. New results from Uppsala University show that such cells are not always what they are assumed to be. Using genetic analyses, the researchers showed that a commonly used cell line which was established in Uppsala almost fifty years ago does not originate from the patient it is claimed to stem from.
Many people suffer from anxiety and fears, and a common treatment for these problems is exposure therapy. In a new study published in Current Biology, researchers at Uppsala University have shown how the effect of exposure therapy can be improved by disrupting the recreation of fear-memories in people with arachnophobia.
In a study from Uppsala University, published in the American journal JAMA Cardiology, the fatty acid linoleic acid (Omega 6) in subcutaneous adipose tissue was linked to lower mortality among older men followed over a 15-year period.
The use of smartphones and tablet computers during evening hours has previously been associated with sleep disturbances in humans. A new study from Uppsala University now shows that daytime light exposure may be a promising means to combat sleep disturbances associated with evening use of electronic devices. The findings are published in the scientific journal Sleep Medicine.
For the first time, researchers have revealed the nanostructure of the mesoporous magnesium carbonate Upsalite® and pore size control was achieved without organic templates or swelling agents. By controlling the pore structure of the material the amorphous phase stabilisation exerted on poorly soluble drug compounds can be tuned and the drug delivery rate can be tailored.
Men with blood cells that do not carry the Y chromosome are at greater risk of being diagnosed with Alzheimer’s disease. This is in addition to an increased risk of death from other causes, including many cancers. These new findings by researchers at Uppsala University could lead to a simple test to identify those at risk of developing Alzheimer’s disease.
A simple paper sheet made by scientists at Uppsala University can improve the quality of life for millions of people by removing resistant viruses from water. The sheet, made of cellulose nanofibers, is called the mille-feuille filter as it has a unique layered internal architecture resembling that of the French puff pastry mille-feuille (Eng. thousand leaves).
A new study from Uppsala University shows that compared to non-shift workers, shift workers needed more time to complete a test that is frequently used by physicians to screen for cognitive impairment. However, those who had quit shift work more than five years ago completed the test just as quick as the non-shift workers. The findings are published in the journal Neurobiology of Aging.
In just a few decades, the number of overweight and obese adults and children in the world has reached alarming levels, not least in low-income countries. This year, Uppsala Health Summit is taking place in conjunction with World Obesity Day: 11-12 October 2016. International experts on child obesity will gather to discuss countermeasures with industry, policy makers and society.
Brain tumours in dogs are strikingly similar to their human tumour counterparts. In a recent study in the journal PLOS Genetics, researchers at Uppsala University and Swedish University of Agricultural Sciences have used genetic analyses in different dog breeds to identify genes that could have a role in the development of brain tumours in both dogs and human.
Atrial fibrillation increases the risk of stroke. Treatment with oral anticoagulation reduces this risk but instead increases the risk of bleeding. Today, a new blood test based tool enabling better and more individualized stroke prevention treatment is presented at a congress in Chicago, and simultaneously published in the top-ranked medical journal The Lancet.
Cancer therapy is often hampered by the accumulation of fluids in and around the tumour, which is caused by leakage from the blood vessels in the tumour. Researchers at Uppsala University now show how leakage from blood vessels is regulated. They have identified a novel mechanism whereby leakage can be suppressed to improve the result of chemotherapy and reduce the spread of tumours in mice.
For the first time, researchers have succeeded in passing an antibody through the blood-brain barrier to act as a tracer for PET imaging of the brain. This resulted in more precise information being obtained than with regular radioactive tracers. The study provides hope for more effective diagnosis of early onset Alzheimer’s disease and improvements in monitoring the effects of medication.
Individuals subjected to chronic low-dose exposure to organochlorine pesticides show and increased risk to obtain a future diagnosis of cognitive impairment. This is shown in a international study now published in Environmental International.
A new study shows that a novel imaging-based method for defining appropriateness of breast cancer treatment is as accurate as the current standard-of-care and could reduce the need for invasive tissue sampling. The results suggest that the method might lead to more optimal treatment of individual patients.
Now a simple blood test can reveal your biological age—how old your body really is. The new research from Uppsala University is published in the Open Access journal Scientific Report@Nature today. ‘With this knowledge, it may be easier to motivate medical treatments or get a patient to change lifestyle and monitor the effect,’ says one of the authors, Professor Ulf Gyllensten.
The press release "Posttraumatic stress disorder reveals an imbalance between signalling systems in the brain" is cancelled. Embargo until December 1st at 9.00 GMT
A team of Swedish scientists have used national registries encompassing more than one million Swedish children to study the association between early life contact with dogs and subsequent development of asthma. The new study found that children who grew up with dogs had about 15 percent lower risk of asthma than children without dogs.
One of the major global healthcare challenges today is the increasing prevalence of obesity and overweight caused by unhealthy diets. The steering committee of the Uppsala Health Summit has decided that this pressing issue is to be the focus of next year’s Uppsala Health Summit.