Retroviruses are important pathogens capable of crossing species barriers to infect new hosts, but knowledge of their evolutionary history is limited. By mapping endogenous retroviruses (ERVs), researchers at Uppsala University, Sweden, can now provide unique insights into the evolutionary relationships of retroviruses and their host species.
It was previously thought that the two test methods signalled the same type of asthma. But a new study, led by researchers at Uppsala University, Sweden, shows that the methods actually signal two different inflammatory processes. With the tests used in combination, the chances are probably greater for the patient to receive just the right treatment.
Why many diseases lead to calcifications in the brain is not known. New insights into the genetic causes of familial idiopathic basal ganglia calcification (FIBGC), also referred to as Fahr’s disease, pinpoint brain pericytes and a defective blood-brain barrier (BBB) as likely culprits in brain calcification. The findings were recently published in the journal Nature Genetics.
Researchers at Uppsala University and Yale University have identified a new mutation in adrenal gland tumor cells as a probable cause of hypertension. The findings were recently published in the journal Nature Genetics.
A new study reveals that all children with Crohn’s disease that were examined had a commonly occurring virus – an enterovirus – in their intestines. This link has previously not been shown for this chronic inflammatory intestinal disorder. The findings are being published today in the latest issue of the international journal Clinical and Translational Gastroenterology.
An international research team led by Swedish scientists has used a new method to investigate obesity and overweight as a cause of cardiovascular disease. Strong association have been found previously, but it has not been clear whether it was overweight as such that was the cause, or if the overweight was just a marker of another underlying cause.
How cells regulate their own function by “accelerating and braking” is important basic knowledge when new intelligent medicines are being developed, or when plant cells are tweaked to produce more bioenergy. In a study published by Nature Communications 14 May, researchers at Uppsala and Umeå universities, Sweden, show a model of how cells’ regulatory systems work.
Community groups in rural Vietnam comprised of local health workers, politicians and laywomen (Maternal and Newborn Health Groups) set up to tackle challenges to maternal and neonatal health may reduce the neonatal death rate after three years and increase antenatal care attendance, according to a study by researchers from Sweden and Vietnam published in this week’s PLOS Medicine.
A novel gene associated with canine atopic dermatitis has been identified by a team of researchers led by professors at Uppsala University and SLU, Sweden. The gene encodes a protein called plakophilin 2, which is crucial for the formation and proper functioning of the skin structure, suggesting an aberrant skin barrier as a potential risk factor for atopic dermatitis.
An international research team has identified seven new gene loci linked to obesity. Researchers were also able to show that the genetic mechanisms that cause extreme obesity are similar to those that cause milder forms of overweight and obesity.
Collaboration between medical and anthropological expertise can solve complex clinical problems in today's multicultural women's healthcare, shows Pauline Binder, a medical anthropologist, who will present her thesis on 1 December at the Faculty of Medicine, Uppsala University.
How new genes arise poses a fundamental biological question. New findings by researchers at Uppsala University and in the US show that it is possible to get new genes to develop in a laboratory environment using a rapid, stepwise process where an already existing gene with multiple functions is initially amplified.
Newly formed emotional memories can be erased from the human brain. This is shown by researchers from Uppsala University in a new study now being published by the academic journal Science. The findings may represent a breakthrough in research on memory and fear.
The potential value of biobank research is immense. But why should you contribute? In a doctoral thesis from Uppsala University, Joanna Stjernschantz Forsberg claims that we have a moral duty to take part in biobank research.
The congenital eye disease persistent foetal vasculature syndrome leads to bleeding, detached retina, and a cloudy lens. Now researchers at Uppsala University show in a model for the disease that it may be associated with an excessive expression of a growth factor during the foetal period.
Adrenocortical cancer is an uncommon form of cancer that is often fatal. For the first time, a large-scale randomized treatment study has now been carried out. The study is being published in the prestigious New England Journal of Medicine and constitutes an important and long-awaited platform for continued research.
There is a correlation between high levels of the environmental toxin PCB and the distribution of body fat to the abdomen. This is shown in a new study published today in the scientific journal Obesity. Abdominal fat is already known to increase the risk of diabetes and high blood pressure, among other conditions.
The devastating role of maternal and child malnutrition is especially prominent in South Asia. In this week’s issue of JAMA researchers from Uppsala University in collaboration with colleagues from Bangladesh and United States report significant progress in reducing the consequences of malnutrition in pregnant women.
New research from Uppsala University, Sweden, suggests that an active lifestyle in late life protects grey matter and cognitive functions in humans. The findings are now published in the scientific journal Neurobiology of Aging.
Paediatric brain tumours preserve specific characteristics of the normal cells from which they originate – a previously unknown circumstance with ramifications for how tumour cells respond to treatment. This has been shown by Uppsala researcher Fredrik Swartling together with colleagues in the U.S., Canada and England in a study that was published today in the distinguished journal Cancer Cell.