Men with blood cells that do not carry the Y chromosome are at greater risk of being diagnosed with Alzheimer’s disease. This is in addition to an increased risk of death from other causes, including many cancers. These new findings by researchers at Uppsala University could lead to a simple test to identify those at risk of developing Alzheimer’s disease.
A new study from Uppsala University shows that compared to non-shift workers, shift workers needed more time to complete a test that is frequently used by physicians to screen for cognitive impairment. However, those who had quit shift work more than five years ago completed the test just as quick as the non-shift workers. The findings are published in the journal Neurobiology of Aging.
Brain tumours in dogs are strikingly similar to their human tumour counterparts. In a recent study in the journal PLOS Genetics, researchers at Uppsala University and Swedish University of Agricultural Sciences have used genetic analyses in different dog breeds to identify genes that could have a role in the development of brain tumours in both dogs and human.
Atrial fibrillation increases the risk of stroke. Treatment with oral anticoagulation reduces this risk but instead increases the risk of bleeding. Today, a new blood test based tool enabling better and more individualized stroke prevention treatment is presented at a congress in Chicago, and simultaneously published in the top-ranked medical journal The Lancet.
Cancer therapy is often hampered by the accumulation of fluids in and around the tumour, which is caused by leakage from the blood vessels in the tumour. Researchers at Uppsala University now show how leakage from blood vessels is regulated. They have identified a novel mechanism whereby leakage can be suppressed to improve the result of chemotherapy and reduce the spread of tumours in mice.
Individuals subjected to chronic low-dose exposure to organochlorine pesticides show and increased risk to obtain a future diagnosis of cognitive impairment. This is shown in a international study now published in Environmental International.
A new study shows that a novel imaging-based method for defining appropriateness of breast cancer treatment is as accurate as the current standard-of-care and could reduce the need for invasive tissue sampling. The results suggest that the method might lead to more optimal treatment of individual patients.
Now a simple blood test can reveal your biological age—how old your body really is. The new research from Uppsala University is published in the Open Access journal Scientific Report@Nature today. ‘With this knowledge, it may be easier to motivate medical treatments or get a patient to change lifestyle and monitor the effect,’ says one of the authors, Professor Ulf Gyllensten.
A team of Swedish scientists have used national registries encompassing more than one million Swedish children to study the association between early life contact with dogs and subsequent development of asthma. The new study found that children who grew up with dogs had about 15 percent lower risk of asthma than children without dogs.
By detecting cancer at an early stage, or even predicting who has an increased risk of being affected, the possibilities to treat the disease can be radically improved. In an international study led from Uppsala University the researchers have discovered that apparently healthy breast cells contain genetic aberrations that can be associated with an increased risk for non-familial breast cancer.
Researchers from Uppsala University, Sweden, and the Broad Institute, USA, have identified both similarities and differences between a single tumour type in multiple dogs breeds; a finding they believe parallels the situation in the cancer of human patients.
After the genocide in the mid-1990s, Rwanda initiated major social and health reforms to improve the survival of all children. In his dissertation, Aimable Musafili from Uppsala University and the University of Rwanda reports an impressive decline in child mortality in Rwanda and disappearing social divides in child survival.
A new smart research robot accelerates research on cancer treatments. The new robot system finds optimal treatment combinations. Today Scientific Reports (Nature Publishing Group) is publishing an article about the robot, authored by Dr Mats Gustafsson, Professor of Medical Bioinformatics at Uppsala University.
Children with cancer want honest but hopeful information. But giving appropriate information is difficult and improvements are needed for the sake of the child, the siblings and the parents. In a dissertation from Uppsala University, Li Jalmsell stresses the need for a family perspective and involvement at the end of the child’s life.
Clinical trials are an important part of cancer research. Future patients depend on the severely ill to test drugs to improve treatment. But in her dissertation from Uppsala University, Tove Godskesen shows that some of these patients have a limited understanding of the purpose of the studies they enroll in.
IgA deficiency is one of the most common genetic immunodeficiency disorders in humans and is associated with an insufficiency or complete absence of the antibody IgA. Researchers from Uppsala University and Karolinska Institutet have now performed the first comparative genetic study of IgA deficiency by using the dog as genetic disease model. The results are published in PLOS ONE.
New research from Uppsala University shows promising progress in the use of anti-inflammatory cytokine for treatment of type 1 diabetes. The study, published in the open access journal Scientific Reports, reveals that administration of interleukin-35 to mice with type 1 diabetes, reverses or cures the disease by maintaining a normal blood glucose level and the immune tolerance.
It is known that sleep facilitates the formation of long-term memory in humans. In a new study, researchers from Uppsala University now show that sleep does not only help form long-term memory but also ensures access to it during times of cognitive stress.
A new technique to study proteins, which does not require advanced equipment, specialized labs or expensive reagents, has been developed at Uppsala University, Sweden. The technique could be further developed to be used in point of care devices, for instance for diagnostic purposes.
New research from Uppsala University shows promising progress in the use of stem cells for treatment of spinal cord injury. The results, which are published in the scientific journal Scientific Reports, show that human stem cells that are transplanted to the injured spinal cord contribute to restoration of some sensory functions.