Researchers at Uppsala University have developed an instrument that makes it possible to measure 21 biomarkers for cardiovascular disease simultaneously with great precision by means of a simple blood test. The aim is to use this type of tool to improve the prediction of cardiovascular complications and facilitate more personalised treatment for patients.
The nuclear accident in Chernobyl in 1986 led to the spread of radioactivity across Sweden and Europe. In a long-term study now published in Environmental Epidemiology, researchers have used new, more specific calculation methods to show the connection between radiation dose and certain types of cancer.
Young children are able to talk in detail about their feelings and how things are at home. They are also good at reading their parents and their emotions by describing their behaviours, facial expressions and tone of voice. This has been shown in a new study by Uppsala University, published in the Journal of Child and Family Studies.
Women with a high genetic predisposition for blood clots are six times more likely to develop a blood clot during the first two years of using contraceptive pills according to a new study from Uppsala University. The results have been published in the American Journal of Obstetrics and Gynaecology.
Contraceptive pills can reduce the risk of rheumatoid arthritis, while hormone treatment in connection with menopause can increase the risk later in life. In a new study of more than 200,000 women in the UK, researchers at Uppsala University have discovered connections between the use of sex hormones and the risk of developing rheumatoid arthritis.
Survival rates for men with metastatic prostate cancer have increased by an average of six months, something which coincides with the gradual introduction of ‘dual treatment’ since 2016. This is according to a register study of all Swedish men diagnosed between 2008 and 2020. The results are published in the medical journal JAMA Network open.
Researchers from Uppsala University have revealed one of the mechanisms behind the growth of cancer cells in the blood cancer multiple myeloma. The study shows that the protein EZH2 interacts with a specific RNA molecule to block genes that are important for tumour growth. The findings might contribute to the development of new treatments for multiple myeloma patients.
The frequency of mast cell progenitors in the blood circulation is higher in asthma patients during the birch pollen season than outside of it. This has been demonstrated in a new study by Uppsala University, published in the scholarly journal Allergy.
Researchers at Uppsala University, Stockholm University and KTH have managed to create a new spatial omics method. By combining two complex techniques that are usually used separately – mass spectrometry imaging (MSI) and spatially resolved transcriptomics (SRT) – they have taken an important step in research on biological tissues. The study is published in the Nature Biotechnology.
In a major Swedish study, researchers have discovered a link between the levels of certain bacteria living in the gut and coronary atherosclerotic plaques. Such atherosclerotic plaques constitute a major cause of heart attacks. The study was led by researchers at Uppsala University and Lund University and the findings have now been published in the scientific journal Circulation.
Many studies have linked obesity to an increased risk of cancer, but most have not differentiated the risks between men and women. In a new study published in Cancer Cell, researchers from Uppsala University takes a closer look at this connection.
A new study has discovered that the pro-viral host protein ZC3H11A has a critical role to maintain embryo viability during early development. The study has uncovered a previously unknown function of ZC3H11A in the intricate process of embryonic growth and highlights its impact on development. The study is led by Uppsala University and INRAE/Université Paris-Saclay, now published in journal PNAS.
In a new study, researchers at Uppsala University have investigated how junk food affects sleep. Healthy participants consumed an unhealthier as well as a healthier diet in a randomised order. After the unhealthier diet, the quality of the participants’ deep sleep had deteriorated, compared with those who had followed the healthier diet. The results have been published in the journal Obesity.
A major international research project, jointly led by Prof Kerstin Lindblad-Toh at Uppsala University and Broad Institute has surveyed and analysed the genomes of 240 different mammals. The results, now published in 11 articles in the journal Science, show how the genomes of humans and other mammals have developed over the course of evolution.
Patients treated with blood pressure-lowering drugs can experience much greater improvements from a change of medication than from doubling the dose of their current medication. This is shown by a new study from Uppsala University, published in the Journal of the American Medical Association. In this study, 280 patients tested four different blood pressure-lowering drugs over the course of a year.
Overweight and obesity among four-year-olds increased during the COVID-19 pandemic, according to a new study by Uppsala University involving over 200,000 children in Sweden. The number of children with obesity increased by some 30 percent, and there are large regional differences. The study was published in the journal Acta Paediatrica.
The use of broad-spectrum antibiotics increased drastically in intensive care at the beginning of the Covid-19 pandemic. At first, this helped patients and seemed to prevent the growth of most bacteria. However, it also contributed to a sharp growth in enterococci, an antibiotic-tolerant group of bacteria, which rendered the treatment of urinary tract infections more difficult.
Thanks to a new prognostic method for detecting cancers including cancer of the large intestine, doctors could provide clearer disease prognoses and predict which patients will respond best to immunotherapy. The method consists of a combination of two types of immune cells that characterise certain forms of cancer. This has been shown in a new study published in the journal eBioMedicine.
The earlier infants begin to taste small samples of solid food, the earlier they eat more food and stop breastfeeding. This is shown in a new study from Uppsala University and Sophiahemmet University, in which the mothers of 1,251 infants from all over Sweden participated. Almost half of the infants received tastings at the age of four months.
Bacterial perseverance is a new phenomenon that helps explain how bacteria adapt to survive antibiotic treatments. A group of researchers at Uppsala University have studied how individual bacteria react when exposed to different antibiotics. The result underlines the importance of adhering strictly to antibiotic prescriptions.