Variety of risk genetic risk factors behind bone cancer in dogs
Bone cancer in dogs is affected by a variety of genetic risk factors. Researchers from Uppsala University and the Broad Institute show this in a new study published in Genome Biology.
Topics: Medicine
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How bacteria respond so quickly to external changes
A research study from Uppsala University, Sweden, is now presenting a model of how bacteria can rapidly adapt to environmental changes through smart regulation of their gene expression. This is important not least for our understanding of resistance to antibiotics.
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New tales told by old infections
Retroviruses are important pathogens capable of crossing species barriers to infect new hosts, but knowledge of their evolutionary history is limited. By mapping endogenous retroviruses (ERVs), researchers at Uppsala University, Sweden, can now provide unique insights into the evolutionary relationships of retroviruses and their host species.
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Two tests in combination can provide better asthma diagnosis
It was previously thought that the two test methods signalled the same type of asthma. But a new study, led by researchers at Uppsala University, Sweden, shows that the methods actually signal two different inflammatory processes. With the tests used in combination, the chances are probably greater for the patient to receive just the right treatment.
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A high price to pay for cheap technology
Rape in war cannot be addressed in isolation. It is deeply embedded in both the local context and that of global proportions. This is one of the conclusions made in a doctoral thesis about eastern Democratic Republic of Congo presented at Uppsala University on 19th September.
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Mechanical chest compressions for cardiac arrest just as good as manual
In the event of cardiac arrest outside of a hospital it is important to provide effective chest compressions without interruption. Creating blood flow reduces the risk of brain damage and improves the chances of survival. A new Swedish study shows that mechanical treatment yields results that are at least as good as manual treatment.
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The ribosome – a new target for antiprion medicines
New research results from Uppsala University, Sweden, show that the key to treating neurodegenerative prion diseases such as mad cow disease and Creutzfeldt-Jakob disease may lie in the ribosome, the protein synthesis machinery of the cell. The results were recently published in the Journal of Biological Chemistry.
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Link shown between Crohn’s disease and virus
A new study reveals that all children with Crohn’s disease that were examined had a commonly occurring virus – an enterovirus – in their intestines. This link has previously not been shown for this chronic inflammatory intestinal disorder. The findings are being published today in the latest issue of the international journal Clinical and Translational Gastroenterology.
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Overweight causes heart failure – large study with new method clarifies the association
An international research team led by Swedish scientists has used a new method to investigate obesity and overweight as a cause of cardiovascular disease. Strong association have been found previously, but it has not been clear whether it was overweight as such that was the cause, or if the overweight was just a marker of another underlying cause.
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Cells must use their brakes moderately for effective speed control
How cells regulate their own function by “accelerating and braking” is important basic knowledge when new intelligent medicines are being developed, or when plant cells are tweaked to produce more bioenergy. In a study published by Nature Communications 14 May, researchers at Uppsala and Umeå universities, Sweden, show a model of how cells’ regulatory systems work.
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Local community group activities may help reduce neonatal mortality in Vietnam
Community groups in rural Vietnam comprised of local health workers, politicians and laywomen (Maternal and Newborn Health Groups) set up to tackle challenges to maternal and neonatal health may reduce the neonatal death rate after three years and increase antenatal care attendance, according to a study by researchers from Sweden and Vietnam published in this week’s PLOS Medicine.
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Researchers identifies gene associated with eczema in dogs
A novel gene associated with canine atopic dermatitis has been identified by a team of researchers led by professors at Uppsala University and SLU, Sweden. The gene encodes a protein called plakophilin 2, which is crucial for the formation and proper functioning of the skin structure, suggesting an aberrant skin barrier as a potential risk factor for atopic dermatitis.
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EU project will increase researcher access to biobanks
All of us stand to benefit from large European health studies, but it is not always easy for researchers to collaborate across national borders. To help enable collaboration, the international EU-funded project BBMRI-LPC will spend the next four years working to increase researchers’ access to samples and data. Researchers at Uppsala University have a key role in the project.
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Genes behind obesity mapped in large-scale study
An international research team has identified seven new gene loci linked to obesity. Researchers were also able to show that the genetic mechanisms that cause extreme obesity are similar to those that cause milder forms of overweight and obesity.
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PCBs can increase risk of lowered heart function
There is a connection between high levels of PCBs and the heart’s ability to pump. The study is the latest of several from the Uppsala University research group showing health issues caused by PCBs, even though their use has been banned for some time.
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New technology platform launched at SciLifeLab in Uppsala
An advanced chip that swiftly and with extremely high sensitivity can measure 92 different tumour proteins from 92 different patients is now available at SciLifeLab in Uppsala. The new technology will become an important resource for researchers and companies developing diagnostics for different illnesses.
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Lack of sleep? Keep away from the buffet
New research from Uppsala University shows that sleep-deprived people select greater portion sizes of energy-dense snacks and meals than they do after one night of normal sleep. Poor sleep habits can therefore affect people’s risk of becoming overweight in the long run. The findings are published in Psychoneuroendocrinology.
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Researchers guardians of trust in biobank research
Do we trust biobank researchers? In a doctoral thesis from Uppsala University, medical doctor and bioethicist Linus Johnsson claims that we do: At least in Sweden. And since we do, researchers in turn have a moral responsibility towards us.
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Ethical challenges of human brain simulation
One of the greatest challenges of modern science is understanding the human brain. Uppsala University’s Centre for Research Ethics & Bioethics (CRB) is part of the European Commission flagship initiative to simulate the human brain and will look at the philosophical and ethical implications of this.
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Anthropological expertise facilitates multicultural women's health care
Collaboration between medical and anthropological expertise can solve complex clinical problems in today's multicultural women's healthcare, shows Pauline Binder, a medical anthropologist, who will present her thesis on 1 December at the Faculty of Medicine, Uppsala University.
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