A new study from SciLifeLab at Uppsala University published in PLOS ONE shows that genes crucial for vision were multiplied in the early stages of vertebrate evolution and acquired distinct functions leading to the sophisticated mechanisms of vertebrate eyes.
In a new study, published in Cell Reports, researchers at Uppsala University describe a novel mechanism by which lymphatic vessels form during embryonic development. The finding may open new possibilities for repairing damaged lymphatic vessels using stem cells.
Retroviruses are important pathogens, which have attacked vertebrate hosts for millions of years. Researchers from Uppsala University and Lund University now provide new knowledge about the long-term interactions of retroviruses and their hosts by analyzing endogenous retroviruses (ERVs), retroviruses whose genes have become part of the host organism’s genome.
In a new study, published in Science, researchers at Uppsala University demonstrate an association between smoking and loss of the Y chromosome in blood cells. The researchers have previously shown that loss of the Y chromosome is linked to cancer. Since only men have the Y chromosome, these results might explain why smoking is a greater risk factor for cancer among men.
The theme for the next Uppsala Health Summit, to be held in Uppsala, Sweden, on 2–3 June 2015, is antibiotic resistance — one of the biggest global health challenges of our day. The basis of the Summit will be the WHO draft Global Action Plan against antimicrobial resistance that is the focus for the high-level meeting starting today in Stockholm, hosted by the Public Health Agency of Sweden.
Scientists from Uppsala University, the Science for Life Laboratory (SciLifeLab) in Stockholm and Uppsala University Hospital have developed a new method of rapidly identifying which bacteria are causing an infection and determining whether they are resistant or sensitive to antibiotics. The findings are now being published in the Journal of Clinical Microbiology.
In a new study published in the scientific journal Oncotarget researchers from Uppsala University show that a therapeutic vaccine directed against tumor vessels can reduce tumor burden and suppress formation of spontaneous lung metastases in a mouse model for metastatic breast cancer.
If chronic lymphocytic leukemia patients with a good or poor prognosis could be identified already at the time of diagnosis, physicians would have better possibilities to adjust their therapeutic and follow-up strategies. Now researchers at Uppsala University have discovered a new correlation between specific molecular features of the disease and subgroups of patients with different prognosis.
Different types of glioma are usually diagnosed as separate diseases and have been considered to arise from different cell types in the brain. Now researchers at Uppsala University have shown that one and the same cell of origin can give rise to different types of glioma.
What does it mean to simulate the human brain? Why is it important to do so? And is it even possible to simulate the brain separately from the body it exists in? These questions are discussed in a new paper published in the scientific journal Neuron today.
New research at Uppsala University shows that plasmids containing genes that confer resistance to antibiotics can be enriched by very low concentrations of antibiotics and heavy metals. These results strengthen the suspicion that the antibiotic residues and heavy metals (such as arsenic, silver and copper) that are spread in the environment are contributing to the problems of resistance.
If we embrace lifestyle changes and new technology, we improve our prospects of staying healthy in old age, getting good care and reducing our dependence on others. This is the message of a new report summarising the conclusions from the conference Uppsala Health Summit in June.
A new Swedish study shows that adolescents who suffer from sleep disturbance or habitual short sleep duration are less likely to succeed academically compared to those who enjoy a good night’s sleep. The results have recently been published in the journal Sleep Medicine.
In a new study published in Nature Communications, research scientists from Uppsala University present for the first time a large-scale study of the significance of genetic, clinical and lifestyle factors for protein levels in the bloodstream. The results of the study show that genetics and lifestyle are determining factors for protein levels.
A new study from Uppsala University demonstrates that elderly humans carrying a common variant of the fat mass and obesity gene FTO also have a shifted endocrine balance. Low blood concentrations of the satiety hormone leptin and high blood concentrations of the hunger promoting hormone ghrelin makes carriers of the FTO gene put on weight. The findings are published in the journal Diabetes.
In a new study, published in Nature Communications today, researchers from the Department of Medical Cell Biology at Uppsala University describe findings that offer new clues as to why insulin secretion might fail in diabetes and open the possibility of discovering novel drugs.
In a new study published today in the journal Plos One, researchers at Uppsala University show that the harmful effect of smoking is aggravated if the person has high blood levels of PCB. This indicates that environmental contaminants interact with other risk factors for various diseases – a field the researchers claim is under-researched.
Get set for 3-4 June: Uppsala University and seven other Swedish actors, has invited politicians, opinion-makers and experts from healthcare, academia and companies to an unconditional and open dialogue on the ways forward in an ageing society. The goal of the Uppsala Health Summit is to move from knowledge to action.
It is generally well known that men have an overall shorter life expectancy compared to women. A recent study, led by Uppsala University researchers, shows a correlation between a loss of the Y chromosome in blood cells and both a shorter life span and higher mortality from cancer in other organs.
Using computer simulations to predict which drug candidates offer the greatest potential has thus far not been very reliable, because both small drug-like molecules and the amino acids of proteins vary so much in their chemistry. Uppsala researchers have now cunningly managed to develop a method that has proven to be precise, reliable and general.