It was long believed that proteins need to be well structured to function, but during the last decade it has become clear that disorder is often crucial for function. Now, a research team at Uppsala University has shed light on how such disordered proteins interact with each other.
The Khoe and San peoples in southern Africa play an important role for our understanding of the evolutionary history of humans. These peoples are directly descended from the first branching of the genealogical tree for today’s humans. This is shown in a study led by Uppsala University and being presented in the Web version of the journal Science today.
The congenital eye disease persistent foetal vasculature syndrome leads to bleeding, detached retina, and a cloudy lens. Now researchers at Uppsala University show in a model for the disease that it may be associated with an excessive expression of a growth factor during the foetal period.
Individuals with elevated levels of PCBs and DDT in their blood run a greater risk of having a stroke. This is shown in a study from Uppsala University that is being published today in the scientific journal Environmental International.
One of the most debated developments in human history is the transition from hunter-gatherer to agricultural societies. This week’s edition of Science presents the genetic findings of a Swedish-Danish research team, which show that agriculture spread to Northern Europe via migration from Southern Europe.
On April 15, a century have passed since the Titanic foundered during its maiden voyage. Since then there has been a widespread belief that in a disaster, women and children will be saved first. Based on analyses of 18 of the most notable shipwrecks from the 19th century until today, researchers from Uppsala University conclude that this is a myth.
Knowledge about the development of the nervous system is of the greatest importance to understand the function of the brain and brain disorders. Researchers at Uppsala University have examined the key step when genes are read and found that genes that are active in the brain are transcribed with a special mechanism. The findings, reported in the journal Nature Structural and Molecular Biology.
An international research team led by Kerstin Lindblad-Toh at the Broad Institute, US and Uppsala University, Sweden has mapped and compared the genomes of 29 mammals. The findings, published in Nature, reveal millions of new regulatory elements in the human genome. The new knowledge is important for our understanding of how mutations in human genes give rise to diseases.