Survival rates for men with metastatic prostate cancer have increased by an average of six months, something which coincides with the gradual introduction of ‘dual treatment’ since 2016. This is according to a register study of all Swedish men diagnosed between 2008 and 2020. The results are published in the medical journal JAMA Network open.
An international team of researchers has released a study on contemporary evolutionary change in natural populations. Their study uses one of the largest genomic datasets ever produced for animals in their natural environment, comprising nearly 4,000 Darwin’s finches. The study has revealed the genetic basis of adaptation in this iconic group. The results are published in the journal Science
A new DNA study has nuanced the picture of how different groups intermingled during the European Stone Age, but also how certain groups of people were actually isolated. The study was carried out by researchers at Uppsala University working with an international team of researchers, who produced new genetic data from 56 Central and Eastern European individuals from the Stone Age.
The use of short flashes of X-ray light brings scientists one big step closer toward developing better catalysts to transform the greenhouse gas methane into a less harmful chemical. The result, published in the journal Science, reveals for the first time how carbon-hydrogen bonds of alkanes break and how the catalyst works in this reaction.
Scientists from Uppsala University have used cryo-electron microscopy to reveal details of the protein synthesis mechanism in the parasite Giardia intestinalis, which causes diarrhoeal disease. The new insights could be valuable for screening specific drugs against Giardia and other protozoan parasites.
Bacterial perseverance is a new phenomenon that helps explain how bacteria adapt to survive antibiotic treatments. A group of researchers at Uppsala University have studied how individual bacteria react when exposed to different antibiotics. The result underlines the importance of adhering strictly to antibiotic prescriptions.
Researchers from Uppsala University and elsewhere have been studying the effect of rising temperatures on the lifespan of pollinating fig wasps. The findings show that the wasps lived much shorter lives at high temperatures, which would make it difficult for them to travel the long distances between the trees they pollinate.
In a study an international team of researchers have identified 28 gene regions that have been particularly important in the evolution of Darwin’s finches. These genetic variants do not represent recent mutations but constitute ancestral genetic variation that has accumulated over time as different species of Darwin’s finches have evolved with striking differences in beak morphology.
A new study combining archaeological, historical and bioarchaeological data provides new insights into the early Islamic period in modern-day Syria. The research team was planning to focus on a much older time period but came across what they believe to be remains of early Muslims in the Syrian countryside.
Lava domes form at the top of many volcanoes when viscous lava erupts. When they become unstable, they can collapse and cause a hazard. An international team of researchers has analysed summit dome instabilities at Merapi Volcano, Indonesia. The researchers hope that by understanding the inner processes, volcano collapses can be better forecasted.
The asteroid which killed nearly all of the dinosaurs struck Earth during springtime. This conclusion was drawn by an international team of researchers after having examined thin sections, high-resolution synchrotron X-ray scans, and carbon isotope records of the bones of fishes that died less than 60 minutes after the asteroid impacted. The team presents its findings in the journal Nature.
An African man who lived just 350 years ago was buried in a prehistoric shell midden in Amoreira in Portugal, well known by archaeologists for the cemeteries of the last hunter-gatherers living in the area, 8 000 years-ago. To investigate this burial researchers from Uppsala University and Universidade de Lisboa combined biomolecular archaeology, ancient DNA, and historical records.
By linking human population studies with experiments in cell and animal models, researchers have provided evidence that complex mixtures of endocrine disrupting chemicals impact children’s brain development and language acquisition. With their novel approach, the scientists show that up to 54 per cent of pregnant women were exposed to experimentally defined levels of concern.
A new study, led by researchers at Uppsala University, shows that all individual patients suffering from severe COVID-19 may have lower oxygen requirements than was formerly believed. The study was conducted at a Swedish district hospital during the first wave of the pandemic in 2020. The scientists’ methods, as well as their results, may be useful for future planning of health care and resources.
By drilling deep down into sediments on the ocean floor researchers can travel back in time. A research team led from Uppsala University now presents new clues as to when and why a period often referred to as the ‘biogenic bloom’ came to an abrupt end. Changes in the shape of the Earth's orbit around the Sun may have played a part in the dramatic change.
Increasing mental ill health is one of the most urgent public health challenges in the world. The global meeting Uppsala Health Summit, to be held online on 18–21 October, will discuss which preventive measures societies should deploy to better address this troubling trend.
The availability of prey and the ability to adapt to changing environments played key roles in the evolution of sharks. A new study, in which over 3,000 shark teeth were analysed, provides new insight into how modern shark communities were established. The results are published in the journal Current Biology.
Changes in individual cancer cells over time may explain why brain tumours develop so differently, and why some cancer cells are resistant to certain treatments. To track the development of cancer cells, researchers at Uppsala University have devised a new method that, in the long term, may make it easier to develop new, effective drug combinations.
How the cell can mend broken DNA using another DNA copy as template has puzzled researchers for years. How is it possible to find the correct sequences in the busy interior of the cell? Researchers from Uppsala university have now discovered the solution; it is easier to find a rope than a ball if you are blindfolded.
An international team of researchers used historical museum collections to study the effects of human-made antibiotics over the entire history of their application. They found that the increased use of antibiotics in medicine and agriculture in the 1950-1990s led to increases in antibiotic resistance in wild Swedish brown bears. However, the latest 20 years show a downward trend in resistance.
