Researchers at Uppsala University have identified a promising therapeutic approach for the challenging blood cancer multiple myeloma. In a new preclinical study, they demonstrate that a dual treatment with drugs that inhibit epigenetic regulation reduces tumour growth and induces cancer cell death.
For the first time, spin waves also known as magnons, have been directly observed at the nanoscale. This breakthrough was made possible by combining a high–energy-resolution electron microscope with a theoretical method developed at Uppsala University. The results open exciting new opportunities for studying and controlling magnetism at the nanoscale.
An international research team led from Uppsala University has identified new mechanisms behind how the aggressive brain tumour glioblastoma spreads in the brain. Targeting the identified connection between the tumour invasion routes and the tumour cell states could be a potential new treatment strategy.
Most men who are treated for prostate cancer according to modern guidelines have good survival rates and the majority of these men will die of causes other than prostate cancer. This is revealed in a new study from Uppsala University published in the Journal of the National Comprehensive Cancer Network. "“We were surprised by how much life expectancy affected the prognosis" says Marcus Westerberg.
Short teaching interventions on disinformation have no long-term effect on upper secondary school students’ ability to distinguish between credible and misleading news. Strengthening school students’ resilience to disinformation requires more than isolated interventions on source criticism. A new study of 459 Swedish upper secondary school students, is no published in PLOS One.
Targeted training interventions for both health professionals and parents significantly increase the amount of skin-to-skin contact between newborns and their parents in the first 48 hours after birth. The proportion of babies who received nearly 24 hours of skin contact over the first 24 hours increased from 33 per cent to 58 per cent. This is shown in a new study from Uppsala University.
How much an infant cries is largely steered by their genetics and there is probably not much that parents can do about it. This has been shown in a new Swedish twin study from Uppsala University and Karolinska Institutet in which researchers investigated how genetics and environment influence infants’ crying duration, sleep quality and ability to settle during the first months of life.
Giving birth to a child after 40 is becoming more and more common – but it can entail an increased risk to the child. A new study based on data from over 300,000 births in Sweden shows that children of older mothers are more often born prematurely or with complications, especially when the mother is 45 years of age or older.
In large parts of the world, women are having children later and later
With the aid of a 3D printer, researchers at Uppsala University have succeeded in creating a model that resembles human nerve tissue. The model, which can be cultured from the patient’s own cells, makes it possible to test new drug treatments in a lab environment.
Researchers at Uppsala University are questioning the gender-equality paradox. They show that it is not possible to draw the conclusions that women and men in gender-equal countries differ more in their preferences than women and men in less equal countries, from the data studied. "The question is based on Western perspectives and conditions and cannot be applied to other countries"(publ in PNAS)
Thanks to lab-grown miniature intestines, researchers at Uppsala University have successfully mapped how aggressive Shigella bacteria infect the human gut. The study opens the door to using cultured human mini-organs to investigate a wide range of other serious infections.
Heatwaves, droughts and forest fires are some of the extreme climate-related events that are expected not only to become more frequent but also to increasingly strike at the same time. This finding emerges from a new study led by Uppsala University, in which researchers have mapped the impact of climate change in different regions of the world.
Anders Sandrew Foundation donates SEK 50 million over five years (possible extension of a further five) to establish a brand new institute – the Anders Sandrew Institute for Culture and Creativity, and a Chair in Digital Art History. It will concentrate the University’s research in the broad field of culture and creativity, and show the importance of culture for social and community cohesion.
What are the stylistic differences between well-known Swedish authors? And is it possible to distinguish a prestigious writer from a more popular one? The answer is that there seem to be many different ways for authors to capture their audience. This is the conclusion reached by Karl Berglund and Johan Svedjedal, who have used computer-aided analysis to map 20th century Swedish literature.
Uppsala University’s Main Building is one of the few well-preserved intact milieus from the 1880s and has a unique position in Swedish architecture. This applies to both the façade and the entire interior, where the colour scheme, decoration, artworks and furniture have largely remained exactly as they were when the building was inaugurated, writes curator Anna Hamberg in her new thesis.
Researchers from Uppsala Antibiotic Center, Uppsala University and SciLifeLab describe a fundamental mechanism of antibiotic resistance. What happens in a bacterium that is resistant to the antibiotic fusidic acid? With a stop-motion movie at the atomic level, they can show that the resistance protein FusB works nearly like a crowbar. Article published in Nature Communications
Newly discovered fossilised footprints with long toes and claws have been found in a rock slab from Australia. The discovery pushes the origin of reptiles back by 35 million years and overthrows the established evolutionary timeline of backboned land animals. The study, led by researchers at Uppsala University, has been published in the journal Nature.
Even a few nights with insufficient sleep increases promote molecular mechanisms linked to a greater risk of heart problems. This has been shown in a new study in which the researchers investigated how sleep deprivation affects biomarkers (in this case proteins) associated with cardiovascular disease. The study was led from Uppsala University and is published in the journal Biomarker Research.
To provide the right treatment for MS, it is important to know when the disease changes from relapsing-remitting to secondary progressive, a transition that is currently recognised on average three years too late. Researchers at Uppsala University have now developed an AI model that can determine with 90 per cent certainty which variant the patient has.
High-starch algae are important in biofuel production, as a feed supplement in agriculture and as an efficient way to bind carbon dioxide. Researchers have now found a new method to control starch storage in algae - a finding with potential applications in areas such reducing greenhouse gases.
