It was long believed that proteins need to be well structured to function, but during the last decade it has become clear that disorder is often crucial for function. Now, a research team at Uppsala University has shed light on how such disordered proteins interact with each other.
The Khoe and San peoples in southern Africa play an important role for our understanding of the evolutionary history of humans. These peoples are directly descended from the first branching of the genealogical tree for today’s humans. This is shown in a study led by Uppsala University and being presented in the Web version of the journal Science today.
Newly formed emotional memories can be erased from the human brain. This is shown by researchers from Uppsala University in a new study now being published by the academic journal Science. The findings may represent a breakthrough in research on memory and fear.
The potential value of biobank research is immense. But why should you contribute? In a doctoral thesis from Uppsala University, Joanna Stjernschantz Forsberg claims that we have a moral duty to take part in biobank research.
Researchers at Uppsala University have cloned a T-cell receptor that binds to an antigen associated with prostate cancer and breast cancer. T cells that have been genetically equipped with this T-cell receptor have the ability to specifically kill prostate and breast cancer cells. The study is being published this week in PNAS.
Researchers have discovered a mutation in a single gene in horses that is critical for the ability to perform ambling gaits, for pacing and that has a major effect on performance in harness racing. The study, which is published in Nature today, is a breakthrough for our understanding of spinal cord neuronal circuitry and its control of locomotion in vertebrates.
The congenital eye disease persistent foetal vasculature syndrome leads to bleeding, detached retina, and a cloudy lens. Now researchers at Uppsala University show in a model for the disease that it may be associated with an excessive expression of a growth factor during the foetal period.
Individuals with elevated levels of PCBs and DDT in their blood run a greater risk of having a stroke. This is shown in a study from Uppsala University that is being published today in the scientific journal Environmental International.
Last year, the number of armed conflicts in the world increased markedly, with the strongest increase taking place in Sub-Saharan Africa. This is the conclusion in a new report by researchers at the Uppsala Conflict Data Program (UCDP), published in the Journal of Peace Research.
A research team at Uppsala University has managed to clarify how proteins that regulate the activity of genes quickly find their way on chromosomes among millions of possible binding sites. The study also confirms a more than 30-year-old theory about the process. The findings are being published today in the scientific journal Science.
Adrenocortical cancer is an uncommon form of cancer that is often fatal. For the first time, a large-scale randomized treatment study has now been carried out. The study is being published in the prestigious New England Journal of Medicine and constitutes an important and long-awaited platform for continued research.
There is a correlation between high levels of the environmental toxin PCB and the distribution of body fat to the abdomen. This is shown in a new study published today in the scientific journal Obesity. Abdominal fat is already known to increase the risk of diabetes and high blood pressure, among other conditions.
Sweden is a well-functioning, secure, and efficient welfare country. But without a civic registration number, a person quickly winds up entirely outside of everything associated with this. In her dissertation, human geographer Erika Sigvardsdotter has investigated what it means to be undocumented in Sweden, in a legal and social sense and in an existential sense.
The devastating role of maternal and child malnutrition is especially prominent in South Asia. In this week’s issue of JAMA researchers from Uppsala University in collaboration with colleagues from Bangladesh and United States report significant progress in reducing the consequences of malnutrition in pregnant women.
New research from Uppsala University, Sweden, suggests that an active lifestyle in late life protects grey matter and cognitive functions in humans. The findings are now published in the scientific journal Neurobiology of Aging.
Paediatric brain tumours preserve specific characteristics of the normal cells from which they originate – a previously unknown circumstance with ramifications for how tumour cells respond to treatment. This has been shown by Uppsala researcher Fredrik Swartling together with colleagues in the U.S., Canada and England in a study that was published today in the distinguished journal Cancer Cell.
One of the most debated developments in human history is the transition from hunter-gatherer to agricultural societies. This week’s edition of Science presents the genetic findings of a Swedish-Danish research team, which show that agriculture spread to Northern Europe via migration from Southern Europe.
About 300 000 years ago humans adapted genetically to be able to produce larger amounts of Omega-3 and Omega-6 fatty acids. This adaptation may have been crucial to the development of the unique brain capacity in modern humans. In today’s life situation, this genetic adaptation contributes instead to a higher risk of developing disorders like cardiovascular disease.
An international research team has succeeded in identifying a specific kind of dust grain in the vicinity of cool giant stars. This means fresh impetus for Uppsala University researcher Susanne Höfner’s theory about how stars die. In the latest issue of Nature, she discusses the team’s findings.
There is a connection between phthalates found in cosmetics and plastics and the risk of developing diabetes among seniors. Even at a modest increase in circulating phthalate levels, the risk of diabetes is doubled. This conclusion is drawn by researchers at Uppsala University in a study published in the journal Diabetes Care.