The cell of origin in childhood brain tumours affects susceptibility to therapy
Children that are diagnosed with the severe the brain tumour malignant glioma often have a very poor prognosis. New findings from Uppsala University show that in mice glioma development and glioma cell properties are affected by both age and the cell type from which the tumour has arisen. The tumour cell of origin was also important for the susceptibility of the tumour cells towards cancer drugs.