Immunotherapy has proven to be effective against many serious diseases. But to treat diseases in the brain, the antibodies must first get past the obstacle of the blood-brain barrier. In a new study, a research group at Uppsala University describes their development of a new antibody design that increases brain uptake of antibodies almost 100-fold.
It is beneficial to systematise the exchange of information between parents, preschool and child care centres (CHCs) to increase the focus on young children with mental health problems. This is shown in a recently conducted study from Uppsala University, published in the journal PLOS One.
In a study published in the scientific journal Oncotarget, researchers from Uppsala University show how the protein EZH2 affects the development of multiple myeloma, and that inhibition of EZH2 could be used as a new strategy to treat the disease. The tumour form multiple myeloma is today incurable and it has been challenging to improve therapy.
In a new study published in Nature an international research group led from Uppsala University presents the discovery of a group of microbes that provide new insights as to how complex cellular life emerged. The study provides new details of how, billions of years ago, complex cell types that comprise plants, fungi, but also animals and humans, gradually evolved from simpler microbial ancestors.
A recent study from Uppsala University shows how smartphones can be used to make movies of living cells, without the need for expensive equipment. The study is published in the open access journal PLOS ONE, making it possible for laboratories around the world to do the same thing.
Researchers at the Chinese Academy of Sciences in Beijing and Uppsala University, Uppsala, Sweden have put together all known information about the endangered Rufous-headed Robin. Very few observations have been made since it was first discovered in 1905. The researchers suggest that its distribution might be larger than previously thought.
The brain tumour form glioblastoma is difficult to treat and has very poor prognosis. In a new study, published today in the journal Cell Reports, scientists from Uppsala University show that a type of stem cell in the tumour is present in different states, with different response to drugs and radiation. The results may open an avenue towards development of new treatment strategies.
Researchers at the Division of Solid-state Physics and the Division of Material Physics at Uppsala University have shown how the collective dynamics in a structure consisting of interacting magnetic nano-islands can be manipulated. Their findings are published in the scientific journal Scientific Reports
Antibody-based immunotherapy is a new promising method to treat cancer. Unfortunately, today’s treatments can result in adverse side effects. New findings from Uppsala University show an alternative way to administer the therapy, which has the same effect on the tumour but less impact other parts of the body.
Genetic differences in the FADS1 gene and varying ability to produce polyunsaturated fats like omega-3 and omega-6 determine the risk for many different diseases, such as inflammatory diseases and several types of cancer. Scientists at Uppsala University/SciLifeLab in Sweden have clarified this in detail and the work is published in the journal Nucleic Acids Research.
In a new paper, published in Scientific Reports, an international team of researchers has analysed fossils and DNA from living and recently extinct species to show that conservation sensitive Australasian marsupials are much older than previously thought.
Inspired by the way people move at heavy metal concerts, an international team of researchers from Uppsala University and Harvard University have learned how to spot danger zones in mass gatherings before disaster strikes.
In a new study, an international team of researchers made significant progress in visualizing the process how plants split water to produce oxygen. The results are published in Nature.
In a newly published study in The Sociological Review, researchers from Uppsala University and Stockholm University have explored how everyday domestic cooking is part of a self-understanding of men in Sweden and how the expressed sociality of cooking is intertwined with masculinity.
Children that are diagnosed with the severe the brain tumour malignant glioma often have a very poor prognosis. New findings from Uppsala University show that in mice glioma development and glioma cell properties are affected by both age and the cell type from which the tumour has arisen. The tumour cell of origin was also important for the susceptibility of the tumour cells towards cancer drugs.
The mesoporous magnesium carbonate Upsalite® is shown to inhibit growth of Staphylococcus epidermidis, bacteria associated with acne and hospital acquired infections. That is the result of a study published in ACS Omega, by researchers at Uppsala University. The results open up for development of materials inhibiting bacterial growth without the use of antibiotics for e.g. dermal applications.
Cooperating sailfish catch more fish per time than if they hunt individually, a new study from Uppsala University, published in the scientific journal Proceedings of the Royal Society B has shown.
Of the many ecological questions unfolded by climate change, the potential influence of temperature on the feeding preferences of organisms is currently gathering a great deal of attention in the scientific community. In a new study, published in the journal Ecology, researchers show that three species of tadpoles generally increased herbivory under simulated heat wave scenarios.
Since the 18th century, geologists have struggled to explain how big magma chambers form in the Earth’s crust. In particular, it has been difficult to explain where the surrounding rock goes when the magma intrudes. Now a team of researchers from Uppsala University and the Goethe University in Frankfurt have found the missing rocks – and they look nothing like what they expected.
12 specific areas of the DNA sequence are robustly related with the age at which we have our first child, and how many children we'll have during our life. That's the conclusion of a paper published in Nature Genetics today. The study is led by the University of Oxford, University of Groningen, and Uppsala University. It includes analysisis for almost 330,000 people.