In rheumatoid arthritis, antibodies are formed that affect the inflammation in the joints. In an article published today in the journal Annals of the Rheumatic Diseases, researchers at Uppsala University show that antibodies against the cartilage protein collagen II are associated with a good prognosis.
With their measurements and samples, nearly 3,500 schoolchildren have assisted a research study on lakes and global warming, now published in the journal Scientific Reports. The results show that water temperatures generally remain low despite the air becoming warmer. This helps to curb the emission of greenhouse gases.
Household electricity use falls by more than 30% when residents are obliged to pay for their own personal consumption. This is shown in a new study by researchers at Uppsala University’s and the Research Institute of Industrial Economics (IFN), published in the Proceedings of the National Academy of Sciences of the USA (PNAS).
When many genes regulate a single trait, they commonly work together in large clusters or ‘networks’. Taking this into account allows better predictions of how an individual’s genetic make-up affects the trait concerned. The risk of perceiving the importance of an individual gene incorrectly is also reduced.
The history of people and landscapes, whether natural or cultural, is fundamentally connected. Answering key historical questions about this relation will allow us to approach our most important environmental issues in novel ways. Today in the open access journal PLOS ONE archeologists present a list of 50 priority issues for historical ecology.
A new study, looking at the sex-specifically inherited X chromosome of prehistoric human remains, shows that hardly any women took part in the extensive migration from the Pontic-Caspian Steppe approximately 5,000 years ago. The great migration that brought farming practices to Europe 4,000 years earlier, on the other hand, consisted of both women and men.
In a collaborative effort, researchers at Uppsala and Umeå University now show that the formation of methylmercury in sediment is controlled by the molecular composition of the organic matter. The study has been published in Nature Communications.
Researchers have now found an explanation for what triggered the largest volcanic eruption witnessed by humankind. The volcano’s secret was revealed by geochemical clues hidden inside volcanic quartz crystals.
Patients with glioblastoma have very poor prognosis since there are no effective therapies. In a study published in Cell Reports, researchers at Uppsala University have discovered a correlation between the cell type from which the tumour originates and the growth and drug sensitivity of the tumour.
In a new study, researchers at Uppsala University have found evidence of that climate change upends selection of face characteristics in the collared flycatcher. During the study the annual fitness selection on forehead patch size switched from positive to negative, a reversal that is accounted for by rising spring temperatures at the breeding site.
In a new study, researchers at Uppsala University have found evidence of a new principle for how epigenetic changes can occur. The principle is based on an enzyme, tryptase, that has epigenetic effects that cause cells to proliferate in an uncontrolled manner.
When clamping of the umbilical cord is delayed, iron deficiency up to six months of age can be prevented, according to a new study from Uppsala University, published in JAMA Pediatrics. The study was conducted in Nepal.
Immunotherapy has proven to be effective against many serious diseases. But to treat diseases in the brain, the antibodies must first get past the obstacle of the blood-brain barrier. In a new study, a research group at Uppsala University describes their development of a new antibody design that increases brain uptake of antibodies almost 100-fold.
It is beneficial to systematise the exchange of information between parents, preschool and child care centres (CHCs) to increase the focus on young children with mental health problems. This is shown in a recently conducted study from Uppsala University, published in the journal PLOS One.
In a study published in the scientific journal Oncotarget, researchers from Uppsala University show how the protein EZH2 affects the development of multiple myeloma, and that inhibition of EZH2 could be used as a new strategy to treat the disease. The tumour form multiple myeloma is today incurable and it has been challenging to improve therapy.
In a new study published in Nature an international research group led from Uppsala University presents the discovery of a group of microbes that provide new insights as to how complex cellular life emerged. The study provides new details of how, billions of years ago, complex cell types that comprise plants, fungi, but also animals and humans, gradually evolved from simpler microbial ancestors.
A recent study from Uppsala University shows how smartphones can be used to make movies of living cells, without the need for expensive equipment. The study is published in the open access journal PLOS ONE, making it possible for laboratories around the world to do the same thing.
Researchers at the Chinese Academy of Sciences in Beijing and Uppsala University, Uppsala, Sweden have put together all known information about the endangered Rufous-headed Robin. Very few observations have been made since it was first discovered in 1905. The researchers suggest that its distribution might be larger than previously thought.
The brain tumour form glioblastoma is difficult to treat and has very poor prognosis. In a new study, published today in the journal Cell Reports, scientists from Uppsala University show that a type of stem cell in the tumour is present in different states, with different response to drugs and radiation. The results may open an avenue towards development of new treatment strategies.
Researchers at the Division of Solid-state Physics and the Division of Material Physics at Uppsala University have shown how the collective dynamics in a structure consisting of interacting magnetic nano-islands can be manipulated. Their findings are published in the scientific journal Scientific Reports
