Uppsala University researchers have devised a new model for the Universe – one that may solve the enigma of dark energy. Their new article, published in Physical Review Letters, proposes a new structural concept, including dark energy, for a universe that rides on an expanding bubble in an additional dimension.
The critically endangered Grauer’s gorilla has recently lost genetic diversity and has experienced an increase in harmful mutations. These conclusions were reached by an international team of researchers who sequenced eleven genomes from eastern gorilla specimens collected up to 100 years ago, and compared these with genomes from present-day individuals. Results are published in Current Biology.
Isolated human hepatocytes are essential tools in preclinical and clinical liver research, but cell quality is highly variable. Now, researchers from Uppsala University have devised a simple protocol that improves hepatocyte quality and enables cells from a wider quality spectrum to be used in standard and advanced cell culture. The findings are published in Archives of Toxicology.
Otherwise healthy men with advanced prostate cancer may benefit greatly from surgery, but many with this diagnosis have no need for it. These conclusions were reached by researchers after following a large group of Scandinavian men with prostate cancer for 29 years. The results are now published in The New England Journal of Medicine.
For nearly 100 years biologists have argued about how exactly natural selection can possibly work. If nature selects the individuals with the best genes then why aren’t all organisms the same? Recent findings made at Uppsala University suggest that the answer could be sex.
The White-browed Shortwing has been considered to be a single species. But now the mainland and Taiwan Island populations have been studied by an international team of researchers, led by Uppsala University. They analysed DNA, plumages, structure, songs and geographical distributions, and concluded that the continental and Taiwanese populations are actually three rather than one species.
Using DNA sequences for 402 of the 452 species of the world’s “babblers”, an international team from China, Sweden, Denmark, Switzerland and the USA have analysed the evolutionary relationships among these species. Many of these species have not previously been studied using genetic methods, and this is by far the most comprehensive analysis of this group of birds to date.
During the Triassic period mammal-like reptiles called therapsids co-existed with ancestors to dinosaurs, crocodiles, mammals, pterosaurs, turtles, frogs, and lizards. Researchers at Uppsala University in Sweden, together with colleagues in Poland, have discovered fossils from a new genus of gigantic dicynodont. The new species Lisowicia bojani is described in the journal Science.
When deciding not to resuscitate patients in cardiac arrest, ethical issues arise. Nurses and physicians conflicting perspectives often cause frustration. In a new doctoral thesis from Uppsala University, Mona Pettersson examines clinical and ethical perspectives on “DNR orders” in cancer care.
An international team of drought scientists show that while many dams and reservoirs are built, or expanded, to alleviate droughts and water shortages, they can paradoxically contribute to make them worse. The study is published in Nature Sustainability.
In a new article published in Nature an international research team presents high-resolution images of photosystem II, the protein complex that splits water into hydrogen ions and oxygen during photosynthesis. The images will help researchers better understand this complex mechanism, possibly opening up the door to developing cheap and efficient solar fuel devices.
Norse World is a new database which will make it easier for researchers to study perceptions of the surrounding world in Medieval Scandinavian literature. The new tool is a digital resource aimed at researchers in fields such as language history and philology, comparative literature, manuscript studies and digital humanities. It will be freely available to both researchers and the public.
Through random mutation the sequences of our proteins slowly change over time, usually without affecting function. But sometimes new functions will be invented in this process. Scientists at Uppsala University have studied such a case in molecular detail. The results are published in Science Advances and show how several factors conspire to shape a plastic protein-protein interaction.
Selfish genes are genes that are passed on to the next generation but confer no advantage on the individual as a whole, and may sometimes be harmful. Researchers at Uppsala University have, for the first time, sequenced (or charted) two selfish genes in the fungus Neurospora intermedia that cause fungal spores to kill their siblings.
Retroviruses have colonised vertebrate hosts for millions of years by inserting their genes into host genomes, enabling their inheritance through generations as endogenous retroviruses (ERVs). Researchers from Uppsala University now provide new knowledge about the long-term associations of retroviruses and their hosts by studying ERV variation and segregation in wild and domestic rabbits.
In a new scientific article, researchers at Uppsala University describe how, using a completely new method, they have synthesised an artificial enzyme that functions in the metabolism of living cells. These enzymes can utilise the cell’s own energy, and thereby enable hydrogen gas to be produced from solar energy.
Star polymers are within the most topologically entangled macromolecules. With a simulation over a hundred times faster than earlier studies, it is demonstrated that the mean square displacement scales with a power law 1/16 in time, instead of the previously assumed zero. It suggests that star polymer motion is the result of two linear relaxations coinciding in time.
Prevailing dogma in biological research holds that the cell’s protein factories, the ribosomes, function the same way in all cells and in all conditions. In an international study with participation from Weill Cornell Medicine and Uppsala University, published today in the journal Cell Reports, the researchers show that this is a truth that seems to not hold true.
How do the large-scale patterns we observe in evolution arise? A new paper in the journal Evolution by researchers at Uppsala University and University of Leeds argues that many of them are a type of statistical artefact caused by our unavoidably recent viewpoint looking back into the past.
Should researchers inform research participants, if they discover genetic disease risks in the participants? The value of complex genetic risk information for individuals is uncertain. In a PhD thesis from Uppsala University, Jennifer Viberg Johansson suggests that this uncertainty needs to be acknowledged by both geneticists and ethicists.