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Topics: Science, technology

  • From living heritage to zombie churches

    Churches are preserved by an antiquarian system that risks killing them instead of keeping them alive. The Swedish State and the Church of Sweden therefore need to define new joint visions and goals to enable the ecclesiastical cultural heritage to be used and developed. This is shown by historian of art Henrik Lindblad in a new doctoral thesis from Uppsala University.

  • Uppsala scientists reveal protein synthesis mechanism in Giardia

    Scientists from Uppsala University have used cryo-electron microscopy to reveal details of the protein synthesis mechanism in the parasite Giardia intestinalis, which causes diarrhoeal disease. The new insights could be valuable for screening specific drugs against Giardia and other protozoan parasites.

  • Oldest sea reptile from Age of Dinosaurs found on Arctic island

    For nearly 190 years, scientists have searched for the origins of ancient sea-going reptiles from the Age of Dinosaurs. Now a team of Swedish and Norwegian palaeontologists has discovered remains of the earliest known ichthyosaur or ‘fish-lizard’ on the remote Arctic island of Spitsbergen.

  • Overweight in children increased during the pandemic

    Overweight and obesity among four-year-olds increased during the COVID-19 pandemic, according to a new study by Uppsala University involving over 200,000 children in Sweden. The number of children with obesity increased by some 30 percent, and there are large regional differences. The study was published in the journal Acta Paediatrica.

  • “You throw up, then you cough, then you feel better or die”

    Detailed images of illness, death and cancelled activities; these were some of the common themes of children’s drawings during the COVID-19 pandemic. A new study from Uppsala University, in which researchers studied 91 drawings made by children aged between 4 and 6, shows that the pandemic affected the children significantly and that they had extensive knowledge about the disease.

  • New artificial model validates antibodies ability to reach the brain

    A research group at Uppsala University has developed a simple and effective artificial blood-brain barrier model that can be used to determine how well antibody-based therapies can enter the brain. Today animal experimentation is the most common method for testing an antibody’s function and the new model could reduce the need for animal testing.

  • Antibiotics hindered treatment of urinary tract bacteria during the pandemic

    The use of broad-spectrum antibiotics increased drastically in intensive care at the beginning of the Covid-19 pandemic. At first, this helped patients and seemed to prevent the growth of most bacteria. However, it also contributed to a sharp growth in enterococci, an antibiotic-tolerant group of bacteria, which rendered the treatment of urinary tract infections more difficult.

  • Combination of immune cells could provide clearer prognoses for cancer

    Thanks to a new prognostic method for detecting cancers including cancer of the large intestine, doctors could provide clearer disease prognoses and predict which patients will respond best to immunotherapy. The method consists of a combination of two types of immune cells that characterise certain forms of cancer. This has been shown in a new study published in the journal eBioMedicine.

  • Early tastings shorten breastfeeding

    The earlier infants begin to taste small samples of solid food, the earlier they eat more food and stop breastfeeding. This is shown in a new study from Uppsala University and Sophiahemmet University, in which the mothers of 1,251 infants from all over Sweden participated. Almost half of the infants received tastings at the age of four months.

  • Perseverant bacteria challenge antibacterial treatment

    Bacterial perseverance is a new phenomenon that helps explain how bacteria adapt to survive antibiotic treatments. A group of researchers at Uppsala University have studied how individual bacteria react when exposed to different antibiotics. The result underlines the importance of adhering strictly to antibiotic prescriptions.

  • How fat takes over the lymph nodes as we age

    A new study from researchers at Uppsala University presents novel findings on why human lymph nodes lose their function with age and the consequences for the effectiveness of our immune system. The article has been published in The Journal of Pathology.

  • Scandinavian wolves carry many harmful mutations

    Researchers at Uppsala University have shown that Scandinavian wolves carry around 100,000 harmful mutations in their genome. As long as the harmful mutations can be compensated by a healthy genetic variant, this does not need to pose a problem. However, as there has been a high level of inbreeding in the wolf population, the occurrence of double harmful variants has increased with each generation

  • Y chromosome loss may be linked to men's increased risk of severe COVID-19

    Men are at an increased risk of a severe bout of COVID-19 compared to women. Researchers at Uppsala University have now shown that this may be due to loss of the Y chromosome in part of their white blood cells. The findings could eventually be used to assess the risk of developing severe COVID-19 and perhaps to improve treatment.

  • Atopic dermatitis in dogs linked to certain parts of the genome

    Using new gene mapping methods, researchers have found connections between atopic dermatitis in dogs and several regions of the genome. Some genes identified coincide with genes linked to similar problems in humans. The filaggrin gene region, for example, which is regarded as the most powerful risk factor for atopic eczema in humans, has now also been linked to this disease in Labrador retrievers.

  • DNA sequence enhances understanding origins of jaws

    Researchers at Uppsala University have discovered and characterised a DNA sequence found in jawed vertebrates, such as sharks and humans, but absent in jawless vertebrates, such as lampreys. This DNA is important for the shaping of the joint surfaces during embryo development.

  • Old World flycatchers’ family tree mapped

    The European robin’s closest relatives are found in tropical Africa. The European robin is therefore not closely related to the Japanese robin, despite their close similarity in appearance. This is confirmed by a new study of the Old World flycatcher family, to which these birds belong. The study comprises 92 per cent of the more than 300 species in this family.

  • Tablet computers make preschool children’s play less creative

    Preschool children's play involving tablets is less creative and imaginative compared to their play involving physical toys. This is shown in a new study by Uppsala University, and the difference is substantial. The results counter occasional claims that new technology would make children more creative. Tha study is published in Learning, Media and Technology.

  • Safe surgical access to the central core of the human cochlea verified

    An team of surgeons and scientists from, among others, Uppsala University has confirmed secure surgical access to the central core of the human cochlea. The research, published in Scientific Reports, is critical to the first in-human trials of new cell, gene and drug therapies for the inner ear, and will assist with treatment for improving hearing loss and deafness over the long-term.

  • A stem cell protein facilitates relapse of pediatric brain tumours

    The malignant brain tumour type medulloblastoma can become resistant to therapy which can cause relapse. Researchers at Uppsala University have discovered a certain protein that makes tumour cells resting and insensitive to radiation treatment. The research group hopes that the results could eventually lead to better treatments for children that have the highest risk to develop relapses.

  • Healthy food systems in focus at Uppsala Health Summit

    Food lies at the heart of both health and sustainable development. This year’s Uppsala Health Summit takes on the challenges associated with our food systems and how to make them healthier, more inclusive, equitable and sustainable.

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